Continuous Artery-Selective Spin Labeling (CASSL) applied to distal branches of intracranial arteries
نویسندگان
چکیده
Introduction Several methods in perfusion imaging are able to image perfusion territories of cerebral arteries [1]. Most of them only allow for labeling of extracranial arteries like leftand right-sided carotids or vertebral arteries. However, a clear delineation of the border between smaller territories is not possible and often impedes a reliable diagnosis, e.g. the distinct allocation of the origin of an embolus. Continuous Artery-Selective Spin Labeling (CASSL) [2] is one technique to image perfusion territories of cerebral arteries. So far, CASSL was only applied to major brain feeding arteries. In this study we optimize key labeling parameters and demonstrate the feasibility of this method to selectively label blood of individual branching intracranial arteries even in the immediate vicinity of other small vessels in-vivo. In stroke patients, especially in patients with embolic stroke the resulting perfusion maps provide important information for therapeutic decisions. Furthermore, this can help to understand the functional significance of vasculopathies in general.
منابع مشابه
Theoretical investigation and optimization of the labeling process in continuous artery-selective spin labeling (CASSL)
Introduction Continuous artery-selective spin labeling (CASSL) [1] is one technique to image perfusion territories of cerebral arteries. To date, CASSL was only applied to major brain feeding arteries, but, recently, empirical findings have demonstrated that this method is even capable of selectively label the blood of individual branching intracranial arteries [2]. However, the exact behavior ...
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